TopoDx
TopoDx, Inc.
TopoDx, Inc. is a biotechnology startup developing a diagnostic tool to combat the global challenge of antibiotic resistance. Spun out of research from Georgia Tech and Emory University, the company's technology aims to rapidly determine antibiotic susceptibility, reducing test times from days to hours. This allows clinicians to make faster, more informed treatment decisions and improve patient outcomes.
Products & Team
Rapid Antibiotic Susceptibility Diagnostic Test
TopoDx is developing a countertop diagnostic device, roughly the size of a large microwave, that houses its core microbial test. The system utilizes white-light interferometry to observe the physical response of bacterial colonies to antibiotics in real-time. By measuring changes in colony topography at the nanometer level, the technology can quickly determine if the bacteria are resistant or susceptible to a specific drug.
The product directly addresses the critical bottleneck of slow diagnostic times in treating infections. By providing rapid results, it enables clinicians to quickly prescribe targeted, effective antibiotics, which can improve patient outcomes, reduce the reliance on broad-spectrum drugs, and help combat the rise of antibiotic-resistant bacteria.
Customers face significant delays with current testing methods, which can take up to five days. This uncertainty leads to the initial use of broad-spectrum antibiotics, potentially contributing to antibiotic resistance and resulting in suboptimal treatment for the patient.