FORE US Bio

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FORE US Bio Inc.

9 Investors
Precision Oncology
PHILADELPHIA, PA

Fore Biotherapeutics, also known as Fore Bio, is a precision oncology firm focused on creating innovative treatment solutions for patients suffering from difficult-to-treat cancers, particularly those with specific genetic mutations associated with established oncology targets. The company aims to bridge the gap in cancer treatment by developing therapies tailored for patients with unaddressed tumor mutations.

Products & Team

Plixorafenib

Oncology DrugSeed

Plixorafenib, previously known as FORE8394, is an investigational next-generation BRAF inhibitor designed to target a broader spectrum of BRAF gene alterations in cancer cells compared to traditional BRAF inhibitors. This next-gen therapy is currently under investigation for its potential in treating various solid tumors and brain malignancies caused by BRAF mutations.

Value Proposition

Plixorafenib offers hope to cancer patients with specific BRAF mutations who currently have limited or no effective treatments by providing a targeted precision medicine approach.

Pain Points

The primary issues addressed include the lack of effective treatments for patients with specific genetic mutations that are not targeted by existing therapies, leading to a significant number of unserved patients with limited options.

Targets a wide range of BRAF alterationsFDA Orphan Drug Designation for brain and CNS malignanciesUndergoing Phase 2 clinical trials
Industry
Biotechnology
Primary business sector
Founded
2025
Year established
Location
PHILADELPHIA, PA
Primary headquarters

Funding History

Total Raised:
$37.4M
E

Equity Offering

April 2025
$46.0M
Target
Progress
81%
Raised
$37.4M
Target
$46.0M
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