Funded startups in Pennsylvania
Every company below filed a Form D with the SEC. Amounts are as reported on the filing, not estimates.
Updated Sep 1, 2026
- Companies
- 51
- Total raised
- $396.2M
- Filings
- 74
- Median round
- $1.4M
- Cities
- 30
Most recent filings
51Myris TherapeuticsBiotech · SharpsburgHigh-payload antibody drug conjugates for cancer
Sep 1, 2026
$500K
Glacian TechnologiesEnergy · State CollegeAI control software for data center cooling
Jul 28, 2026
$150K
Edge AI SolutionsRobotics · HomesteadPortable crawler robot for sewer and water pipe inspection
Jul 16, 2026
—
ShelfmarkAI · PittsburghCamera inspection that catches defects at line speed
Jun 29, 2026
$4.9M
Smith Micro SoftwareSaaS · PittsburghFamily safety apps that mobile carriers white-label
Jun 15, 2026
—
Tolerance BioBiotech · PhiladelphiaStem cell-derived thymus therapies for immune tolerance
Jun 3, 2026
$15.1M
Pipe Force AIInfrastructure · PittsburghRobotic multi-sensor inspection for sewer and gas pipes
May 14, 2026
$150K
ThoroughcareHealthcare · PittsburghChronic care management software for Medicare programs
May 8, 2026
$2.3M
NovaData SolutionsAI · HaverfordInvoice auditing for insurance restoration claims
May 1, 2026
$1.7M
ZypFintech · EastonCross-border payroll and payments for outsourcing firms
Apr 20, 2026
$10K
BCI InnovationsHealthcare · ErieSilent-speech neckband for people who cannot speak aloud
Apr 17, 2026
—
InspectionGoProptech · TyroneScheduling and business software for home inspectors
Apr 8, 2026
$1.1M
Pharma Solutions USA, Inc. DBA LighthouseAIHealthcare · Penn ValleyState license compliance software for pharma companies
Mar 27, 2026
$7.9M
BELA Printing & PackagingOther · Willow GroveCommercial printing, envelopes and packaging
Mar 24, 2026
—
OpZiraHealthcare · MiddletownDark adaptation headset for detecting retinal disease
Mar 17, 2026
$1.1M
coVERVESaaS · LancasterStrategy and impact tracking software for nonprofits
Mar 16, 2026
$75K
OvalaHealthcare · PittsburghReusable bladder support insert for stress incontinence
Mar 16, 2026
$3.3M
TroutwoodFintech · PittsburgFinancial planning app for consumers and advisors
Mar 10, 2026
$2.9M
BioLattice OphthalmicsBiotech · PhiladelphiaSynthetic cornea implant to replace donor tissue
Mar 6, 2026
$575K
NK-One TherapeuticsBiotech · WayneSpinal injection therapy for intractable cancer pain
Mar 4, 2026
$290K
F2MXFranklinStartup company that was incorporated in Lewes, Delaware on November 18…
Mar 2, 2026
$230K
SubVysionInfrastructure · Philadelphia3D maps of buried utilities for excavation crews
Feb 27, 2026
$355K
Traice LabsAI · WayneEarly-stage AI company in Wayne, Pennsylvania building what it calls…
Feb 17, 2026
$1.1M
MyotaCybersecurity · Blue BellRansomware-resilient cyberstorage for business data
Jan 13, 2026
$3.0M
BenerationSaaS · PhiladelphiaBenefits invoice auditing for employers and brokers
Dec 31, 2025
$3.3M
Mussel PolymersBiotech · BethlehemMussel-inspired adhesive that bonds underwater
Dec 31, 2025
$4.8M
Valence TechnologiesFintech · BethlehemWealth management with AI agents for affluent families
Oct 21, 2025
$7.7M
Carnegie Foundry HealthcareHealthcare · MonroevilleSensor-based fall and seizure monitoring for home care
Jul 22, 2025
$1.5M
Aethl BioBiotech · PittsburghOxygen-delivering hydrogels for chronic wound care
Jul 14, 2025
$1.6M
Fore BiotherapeuticsBiotech · PhiladelphiaBRAF inhibitor for brain and solid tumors
Apr 30, 2025
$70.4M
Sentry SecureCybersecurity · West ChesterAccess control, alarms and video surveillance installation
Apr 10, 2025
$4.0M
Voltic ShippingCleantech · LaughlintownSolar-powered electric cargo ships
Apr 8, 2025
$1.3M
Rent|VestProptech · PittsburghResidential property management for owners and investors
Apr 4, 2025
$100K
AkuvoFintech · MalvernLoan collections and credit risk software for lenders
Mar 28, 2025
$3.0M
Praxis Campus Management SoftwareEdtech · PhiladelphiaCampus management software for colleges
Mar 10, 2025
$293K
IllexcorBiotech · HenricoOral drug for sickle cell disease
Mar 8, 2025
$1.0M
Nested AppsSaaS · WayneInnovative technology company that specializes in providing software…
Mar 5, 2025
$2.8M
BiophyAI · PhiladelphiaAI that predicts clinical trial outcomes
Mar 4, 2025
$6.6M
ProsciaHealthcare · PhiladelphiaDigital pathology software for labs
Mar 4, 2025
$35.0M
BobcatBioBiotech · HummelstownCancer-specific T cell therapies
Feb 26, 2025
$5.3M
Return LogicSaaS · MechanicsburgReturns management software for online retailers
Feb 24, 2025
$366K
QualiaOSSaaS · PhiladelphiaAppears to be a technology-focused company, likely operating in the…
Jan 29, 2025
$500K
CreditlyEdtech · Plymouth MeetingCredly is a leading digital credentialing platform that empowers…
Jan 28, 2025
$33.8M
Cornelis NetworksHardware · WayneOmni-Path networking switches for AI and supercomputing
Nov 25, 2024
$112.0M
Nok TherapeuticsBiotech · Cranberry Twp.Natural killer cell therapy for myeloma and bladder cancer
Sep 24, 2024
$751K
Jabez BiosciencesBiotech · Cranberry Twp.Oral pyrimidine-blocking drug for solid and blood cancers
Jun 11, 2024
$31K
Chimeron BioBiotech · PhiladelphiaSelf-amplifying RNA medicines and vaccines
Mar 25, 2024
$12.8M
Contamination Source IdentificationBiotech · HersheyRNA sequencing test that identifies active infections
Apr 19, 2023
$2.1M
Freespace RoboticsRobotics · MonroevilleRobotic storage cube for warehouse order fulfillment
Jan 30, 2023
$6.6M
DoctivityHealthcare · BloomsburgPhysician relationship management software
Apr 14, 2022
$5.8M
Squad TechnologiesConsumer · PhoenixvilleSocial app for health and wellness creators
Sep 28, 2021
$6.1M
All 51 companies · most recent filing first