Biotechnology Startups in Massachusetts

Alzheon, Inc. is a biotechnology company dedicated to developing innovative treatments for Alzheimer's disease. The company focuses on creating therapeutics that aim to slow or halt the progression of Alzheimer's and potentially prevent the onset of clinical symptoms.

Antares Therapeutics, Inc. is a leading specialty pharmaceutical company focused on the creation and commercialization of innovative drug delivery technologies. With a mission to enhance patient experiences associated with injectable medications, the company develops solutions that significantly improve comfort and convenience for individuals requiring regular treatment.

Founded 2025

Carna Biosciences, Inc. is a biotechnology company dedicated to drug discovery and the development of small molecule drugs. The company aims to address unmet medical needs by offering innovative therapeutic solutions in areas where current treatments are either inadequate or non-existent.

Founded 2021

Consano Bio is an early-stage biotechnology startup founded in 2022 and headquartered in Des Moines, Iowa. The company focuses on developing first-in-category biologic therapeutics to treat painful and debilitating orthopedic conditions. Its core strategy is to target the underlying drivers of disease rather than merely addressing symptoms.

Founded 2022

Epicore Biosystems, Inc. is a digital health company that develops and markets wearable microfluidic technology for real-time, non-invasive health and wellness monitoring. Their solutions provide insights into hydration, stress, nutrition, and overall physiological state, enabling personalized health management.

Ernexa Therapeutics Inc. is a biotechnology company focused on developing cell therapy solutions for advanced cancer and autoimmune diseases. They use induced pluripotent stem cells (iPSCs) to create induced mesenchymal stem cells (iMSCs) with unique targeting capabilities, enabling the creation of scalable, off-the-shelf therapies. This method eliminates the need for patient-specific solutions.

Lapix Therapeutics Inc. is a clinical-stage biopharmaceutical company based in Cambridge, MA, dedicated to developing innovative oral therapeutics that restore immune system function for patients with autoimmune diseases. Through a patient-centric approach, Lapix Therapeutics is pioneering treatments that enhance the body's natural immune tolerance.

Lyra Therapeutics, Inc. is a clinical-stage biotechnology company dedicated to developing groundbreaking therapies specifically for chronic rhinosinusitis (CRS), a prevalent inflammatory condition affecting the nasal passages and sinuses. By leveraging innovative technologies, Lyra aims to provide effective solutions for CRS patients who often endure ineffective treatments and potentially invasive surgeries.

Founded 2024

Medici Therapeutics, Inc. is a biotechnology company focused on developing advanced cancer treatments within the immunotherapy sector. The company's primary focus is on advancing tumor-infiltrating lymphocyte (TIL) therapies by leveraging novel insights into cancer immunology, particularly how cancer cells evade immune responses.

Founded 2021

Nanopath Inc is a pioneering molecular diagnostics company headquartered in Cambridge, Massachusetts. The company is dedicated to revolutionizing traditional medical testing approaches, particularly in the domain of women's health, by developing rapid and accurate diagnostic solutions.

Neutrolis Inc. is a clinical-stage biotechnology firm that specializes in developing innovative therapies aimed at autoimmune and inflammatory diseases. The company's unique approach focuses on targeting Neutrophil Extracellular Traps (NETs), which are implicated in tissue damage and chronic inflammation associated with several immune-mediated disorders, such as lupus and dry eye disease, as well as severe complications from conditions like COVID-19.

Newleos Therapeutics, Inc. is a pioneering clinical-stage neuroscience company focused on the innovation of therapies for neuropsychiatric disorders. With a commitment to addressing the pressing unmet needs in mental health, Newleos is dedicated to developing effective tools for anxiety and substance use disorders, impacting millions across the United States.

Founded 2024

Odyssey Therapeutics is a clinical-stage biopharmaceutical company focused on developing novel therapies for autoimmune and inflammatory diseases. The company's strategy involves targeting upstream signaling nodes in the innate immune system to prevent pathological inflammation before it starts, aiming to induce long-lasting remission for patients.

Founded 2021

PhAST Corp. is a biotechnology company specializing in the transformation of infectious disease diagnostics through innovative rapid diagnostic technology. With a focus on minimizing turnaround times for pathogen detection and testing, PhAST Corp. aims to enhance patient care by enabling timely treatment decisions.

Phio Pharmaceuticals Corp. is a biotechnology company specializing in the development of groundbreaking therapeutics, particularly in the field of immuno-oncology. Utilizing their proprietary technology platform, they focus on addressing unmet medical needs to potentially enhance cancer treatment outcomes.

Syntis Bio, Inc. is a pioneering biotechnology company focused on transforming oral therapeutics through innovative solutions targeting the small intestine. By leveraging its proprietary SYNT™ platform, the company enhances the absorption and effectiveness of treatments for prevalent and challenging conditions such as obesity, diabetes, and rare diseases.

Founded 2022

Tectonic Therapeutic, Inc. is a pioneering biotechnology company based in Watertown, Massachusetts, dedicated to the discovery and development of advanced therapeutic proteins and antibodies. The company primarily focuses on harnessing the potential of G-Protein Coupled Receptors (GPCRs), which are integral to numerous biological processes and disease pathways.

Vaxess Technologies, Inc. is a pioneering life sciences company focused on the development of innovative vaccine and therapeutic delivery technologies. Their flagship product, the MIMIX™ platform, is a cutting-edge transdermal patch system that aims to make vaccines and therapeutics more effective and accessible, particularly in challenging environments.