De novo multifunctional biologics platform
Drug discovery platform / preclinical biologics
A computational protein design platform that generates entirely new protein sequences, synthesizes and purifies them in the lab, and tests them functionally in cell and animal models, producing single-agent biologics that engage multiple pathways.
- De novo protein design not bound by natural antibody structures
- Multifunctional molecules that engage several targets or pathways at once
- Can produce agonists that activate pathways, not only blockers
- Design-to-lab-testing cycle stated at under two months
- Four-stage workflow: conceptual design, computational sequence generation, synthesis and purification, functional testing
Built for
Pharmaceutical and biotech partners licensing or co-developing designed biologics, and ultimately patients with complex autoimmune and oncology indications
