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Funded Biotech startups in the US

256 biotech startups in the US have filed a Form D with the SEC and together report $5.63B raised. Sensei Biotherapeutics has the largest latest round, at $348.9M. Amounts are as reported on the filing, not estimates.

Updated Oct 7, 2026
Companies
256
Total raised
$5.63B
Filings
348
Median round
$3.5M
States
30

Most recent filings

256
AxelyfMassachusetts · Chestnut Hill$2.6MOct 7, 2026KaigeneMaryland · Rockville$55.0MSep 30, 2026BioStem TechnologiesFlorida · Pompano Beach$3.0MSep 29, 2026ArkeaBioMassachusetts · Charlestown$15.0MSep 28, 2026Curadel Surgical InnovationsFlorida · Bonita Springs$49.8MSep 18, 2026Tempest TherapeuticsCalifornia · Brisbane$7.5MSep 15, 2026Caspian TherapeuticsCalifornia · San Diego$50.0MSep 8, 2026Hypercell TechnologiesNew York · Ithaca$3.0MSep 8, 2026Myris TherapeuticsPennsylvania · Sharpsburg$500KSep 1, 2026EndurazymesFlorida · The Villages$50KAug 9, 2026InSitu BiologicsMinnesota · Oakdale$1.3MAug 4, 2026Hepion PharmaceuticalsNew Jersey · Red Bank$3.1MJul 31, 2026Superior GenomicsMichigan · Norway$508KJul 30, 2026Conexeu SciencesNevada · Reno$63KJul 23, 2026ORF BiologicsIowa · Tiffin$1.7MJul 23, 2026NextPoint TherapeuticsMassachusetts · Cambridge$33.7MJul 22, 2026Accipiter BiosciencesWashington · Seattle$10.5MJul 21, 2026Integrated BiosciencesCalifornia · Redwood City$68.4MJul 21, 2026Jasper TherapeuticsCalifornia · Redwood City$132.0MJul 21, 2026Mangrove TherapeuticsCalifornia · Sacramento$2.5MJul 21, 2026TheradaptiveMaryland · Frederick$36.2MJul 21, 2026GeorgiamuneMaryland · Gaithersburg$92.7MJul 16, 2026GenomenonMichigan · Ann Arbor$6.0MJul 15, 2026Cue BiopharmaMassachusetts · Boston$50.0MJul 13, 2026Oncotelic TherapeuticsCalifornia · Agoura Hills$712KJul 10, 2026TYBR HealthTexas · Houston$14.4MJul 9, 2026AmlogenyxCalifornia · Novato$10.0MJul 1, 2026PluristyxWashington · Seattle$9.8MJul 1, 2026AdvanCellMassachusetts · Cambridge$218.3MJun 30, 2026Cadrenal TherapeuticsFlorida · Ponte Vedra$8.8MJun 30, 2026Cambrian BioPharmaNew York · New York$123.8MJun 30, 2026NurExone BiologicExosome drug for acute spinal cord injury$442KJun 30, 2026OS TherapiesMaryland · Grasonville$1.6MJun 30, 2026ImmunoVecCalifornia · Los Angeles$12.7MJun 29, 2026Akadeum Life SciencesMichigan · Ann Arbor$2.1MJun 25, 2026Cellular LogisticsWisconsin · Madison$50KJun 25, 2026Imio TechnologiesIllinois · Chicago$6.0MJun 22, 2026MyrtelleNew York · New York$16.7MJun 22, 2026Rapalogix HealthCalifornia · Carlsbad$19.1MJun 22, 2026AcuraStemCalifornia · PasadenaN/AJun 18, 2026Spearhead BioMissouri · Saint Louis$1.2MJun 18, 2026Qlaris BioMassachusetts · Dedham$3.9MJun 12, 2026TETmedicalNew Jersey · Fair Haven$3.5MJun 12, 2026Lycia TherapeuticsCalifornia · South San Francisco$75.0MJun 10, 2026NeOnc TechnologiesCalifornia · Westlake Village$5.0MJun 10, 2026Reservoir NeuroscienceCalifornia · San Francisco$3.0MJun 8, 2026Skybound MedtechTexas · Houston$1.3MJun 8, 2026SonoTheraCalifornia · South San Francisco$125.5MJun 8, 2026Aspira Women's HealthTexas · Austin$1.5MJun 5, 2026Rejuvenate BioCalifornia · San Diego$19.5MJun 3, 2026Tolerance BioPennsylvania · Philadelphia$15.1MJun 3, 2026ContralineVirginia · Charlottesville$55.8MMay 29, 2026ImmunisCalifornia · Irvine$12.0MMay 28, 2026Barricade TherapeuticsTexas · Fort Worth$100KMay 27, 2026Goldenrod TherapeuticsTexas · Houston$3.2MMay 26, 2026Antlia BioscienceCalifornia · Encinitas$6.0MMay 22, 2026OptimeosNew Jersey · Princeton$1.0MMay 22, 2026Cognos TherapeuticsCalifornia · Inglewood$250KMay 21, 2026HCW BiologicsFlorida · Miramar$4.0MMay 21, 2026Biolexis TherapeuticsUtah · Lehi$1.6MMay 20, 2026Senti BiosciencesCalifornia · South San Francisco$10.0MMay 20, 2026X1 BiotechMassachusetts · Needham$40KMay 20, 2026Quince TherapeuticsCalifornia · South San FranciscoN/AMay 18, 2026Restora MedicalCalifornia · Irvine$11.5MMay 18, 2026ThinkBio.AiCalifornia · OntarioN/AMay 18, 2026Portal BiotechnologiesMassachusetts · Arlington$9.0MMay 15, 2026Reprise BiomedicalMinnesota · Plymouth$9.2MMay 14, 2026Kayak TherapeuticsTexas · Austin$11.9MMay 12, 2026OncosynergyConnecticut · Stamford$6.6MMay 11, 2026SentrimedNew Jersey · Mullica Hill$250KMay 8, 2026Illuminare BiotechnologiesNew York · Brooklyn$3.6MMay 7, 2026Remedium BioMassachusetts · Needham$1.5MMay 6, 2026ReelReactorIdaho · Star$500KMay 5, 2026Allyx TherapeuticsConnecticut · New Haven$26.4MMay 4, 2026Majesty TherapeuticsFlorida · Sea Ranch Lakes$100KMay 1, 2026Shuttle PharmaceuticalsMaryland · Gaithersburg$10.0MApr 30, 2026Climb BioMassachusetts · Wellesley Hills$110.1MApr 29, 2026CresilonNew York · Brooklyn$29.0MApr 24, 2026Outlook TherapeuticsNew Jersey · IselinN/AApr 23, 2026AxoftMassachusetts · Cambridge$34.2MApr 22, 2026Mitera BiosciencesWashington · Bellevue$1.1MApr 21, 2026Enveric BiosciencesMassachusetts · Cambridge$5.0MApr 17, 2026EtiraTexas · Dallas$2.3MApr 17, 2026GreenMark BiomedicalMichigan · East LansingN/AApr 14, 2026AdelaCalifornia · Foster City$5.0MApr 10, 2026Terremoto BiosciencesCalifornia · South San Francisco$40.7MApr 10, 2026Pangia BiotechFlorida · Delray Beach$1.6MApr 8, 2026TetrousCalifornia · Sherman Oaks$1.7MApr 8, 2026RLL BioMaryland · Lutherville$2.0MApr 6, 2026PetragenFlorida · Davie$495KApr 5, 2026Bonum TherapeuticsWashington · Seattle$26.9MApr 3, 2026Iambic TherapeuticsCalifornia · San Diego$27.8MApr 1, 2026NovAbGeorgia · Tucker$65KApr 1, 2026Alloy TherapeuticsMassachusetts · Waltham$30.0MMar 31, 2026Stipple BioMassachusetts · Cambridge$65.1MMar 31, 2026Watershed MedicalWashington · Bellevue$300KMar 31, 2026Artelo BiosciencesCalifornia · Solana Beach$11.0MMar 27, 2026PulmatrixMassachusetts · Framingham$1.0MMar 26, 2026Bascule BiosciencesNew York · New Rochelle$250KMar 25, 2026Valius SciencesCalifornia · San Francisco$9.7MMar 25, 2026Alume BiosciencesCalifornia · La Jolla$2.2MMar 24, 2026Iyuda TherapeuticsMaryland · Owings Mills$600KMar 23, 2026DesiCorpKentucky · Louisville$3.5MMar 20, 2026RenovoRxCalifornia · Mountain View$10.0MMar 20, 2026Pearl DiagnosticsMaryland · Baltimore$11.2MMar 19, 2026Canal BiosciencesMassachusetts · Lowell$2.3MMar 18, 2026AptaminoMassachusetts · Cambridge$8.0MMar 17, 2026Reprogram BiosciencesCalifornia · San Carlos$5.0MMar 16, 2026Olden LabsCalifornia · South San Francisco$6.5MMar 13, 2026Vira RegenUtah · Salt Lake CityN/AMar 13, 2026LongeveronFlorida · Miami$15.9MMar 11, 2026PacegenixMassachusetts · Cambridge$22.5MMar 11, 2026Pahtia TechnologiesIndiana · South Bend$45KMar 11, 2026AtomwiseCalifornia · San Francisco$19.8MMar 10, 2026AtommapNew York · New York$31.1MMar 6, 2026BioLattice OphthalmicsPennsylvania · Philadelphia$575KMar 6, 2026Consano BioMassachusetts · Burlington$34.8MMar 6, 2026Dnp TherapeuticsMassachusetts · Cambridge$470KMar 5, 2026NK-One TherapeuticsPennsylvania · Wayne$290KMar 4, 2026Vaxess TechnologiesMassachusetts · Cambridge$57.3MMar 4, 2026Inso BioNew York · Ithaca$750KMar 3, 2026Halcyon WellnessDelaware · Lewes$8.0MFeb 27, 2026Inflammasome TherapeuticsMassachusetts · Newton$13.2MFeb 27, 2026ImmunicNew York · New York$200.0MFeb 17, 2026Sensei BiotherapeuticsMaryland · Rockville$348.9MFeb 17, 2026Jupiter Biomedical ResearchFlorida · Palm Beach Gardens$500KFeb 9, 2026Parcel BiosciencesCalifornia · San Francisco$13.2MFeb 6, 2026Food Supply SecurityColorado · Erie$1.0MFeb 5, 2026Corami BiotechTennessee · Memphis$230KFeb 4, 2026Trellis BioscienceCalifornia · Redwood City$6.1MJan 30, 2026Embold TherapeuticsCalifornia · Redwood City$2.5MJan 21, 2026AirNexis TherapeuticsCalifornia · Palo Alto$62.0MJan 9, 2026Entact BioMassachusetts · Watertown$10.0MJan 8, 2026Mussel PolymersPennsylvania · Bethlehem$4.8MDec 31, 2025Dermata TherapeuticsCalifornia · San Diego$4.1MDec 29, 2025HolobiomeMassachusetts · Boston$10.0MDec 24, 2025CellanomeCalifornia · Foster City$75.9MDec 23, 2025Adaptin BIONorth Carolina · Charlotte$1.9MDec 22, 2025BiostaxFlorida · Winter ParkN/ADec 22, 2025Telos BiotechTexas · Dallas$725KDec 1, 2025Zeo ScientifiXFlorida · Davie$500KNov 30, 2025Medici TherapeuticsMassachusetts · Boston$14.8MNov 20, 2025Arpeggio BiosciencesColorado · Boulder$20.0MNov 12, 2025MedicovestorNew York · New York$3.2MNov 5, 2025Phio PharmaceuticalsMassachusetts · Marlborough$1.4MNov 4, 2025PIPr TherapeuticsNorth Carolina · Durham$1.5MOct 31, 2025Elixirgen TherapeuticsMaryland · Baltimore$4.0MOct 30, 2025CoRegenColorado · Aspen$13.5MOct 28, 2025Pheast TherapeuticsCalifornia · Redwood City$24.6MOct 7, 2025Primary BioscienceWashington · Seattle$1.3MOct 2, 2025GelMEDIXMassachusetts · Cambridge$747KOct 1, 2025ChronicleBioCalifornia · Menlo Park$10.3MSep 30, 2025Nirrin TechnologiesMassachusetts · Billerica$6.7MSep 23, 2025Claris BiotherapeuticsNew Jersey · Jersey City$2.3MSep 12, 2025Mati TherapeuticsTexas · Austin$2.6MSep 12, 2025Dewpoint TherapeuticsMassachusetts · Boston$77.2MSep 9, 2025Tinos TherapeuticsMassachusetts · Cambridge$2.3MSep 4, 2025GliknikMaryland · Baltimore$11.0MAug 15, 2025ValthosNew York · New York$27.3MAug 14, 2025Paralos BioscienceCalifornia · Los Angeles$647KJul 28, 2025Lapix TherapeuticsMassachusetts · Boston$2.2MJul 21, 2025Aethl BioPennsylvania · Pittsburgh$1.6MJul 14, 2025Rakuten MedicalCalifornia · San Diego$111.5MJul 11, 2025Cyrus BiotechnologyWashington · Seattle$1.5MJul 1, 2025Evofem BiosciencesCalifornia · San Diego$925KJun 26, 2025NeutrolisMassachusetts · Cambridge$3.5MJun 20, 2025Syntis BIOMassachusetts · Boston$25.0MJun 17, 2025Odyssey TherapeuticsMassachusetts · Boston$214.0MJun 16, 2025GT BiopharmaCalifornia · San FranciscoN/AMay 14, 2025iOncologiFlorida · Gainsville$250KMay 8, 2025Alpheus MedicalMinnesota · Chanhassen$60.5MMay 2, 2025Fore BiotherapeuticsPennsylvania · Philadelphia$70.4MApr 30, 2025Anavatos BioWashington · Seattle$393KApr 27, 2025Cynaptec PharmaceuticalsFlorida · Stuart$6.0MApr 11, 2025PhASTMassachusetts · Boston$3.5MApr 11, 2025XilisNorth Carolina · Durham$19.4MApr 10, 2025DMC BiotechnologiesColorado · Boulder$4.8MApr 8, 2025Barnwell BioNew York · New York$6.1MApr 4, 2025Zero Point Five TherapeuticsMaryland · Baltimore$4.3MApr 2, 2025Altis BiosystemsNorth Carolina · Durham$2.1MMar 31, 2025Ernexa TherapeuticsMassachusetts · Cambridge$7.2MMar 31, 2025PulmotherapeuticsTexas · Tyler$500KMar 27, 2025Biomark DiagnosticsBlood tests for early lung, breast and pancreatic cancer$2.5MMar 26, 2025SurrozenCalifornia · South San Francisco$76.4MMar 26, 2025Cyclacel PharmaceuticalsNew Jersey · Berkeley Heights$1.0MMar 21, 2025Formulary FinancialConnecticut · Weston$1.7MMar 20, 2025Autonomy BioCalifornia · San Francisco$17.0MMar 17, 2025Cime TherapeuticsColorado · Denver$2.1MMar 14, 2025PanTher TherapeuticsTexas · Austin$3.0MMar 14, 2025Topaz BiosciencesCalifornia · Emeryville$1.4MMar 11, 2025IllexcorPennsylvania · Henrico$1.0MMar 8, 2025Integrity LabsVirginia · Reston$15.0MMar 7, 2025BRT BiotechnologiesCalifornia · Claremont$607KMar 5, 2025DeepkinetiXMassachusetts · Cambridge$1.0MMar 3, 2025Vivace TherapeuticsCalifornia · San Mateo$17.5MFeb 28, 2025Syndex BioCalifornia · Santa Monica$15.5MFeb 27, 2025BobcatBioPennsylvania · Hummelstown$5.3MFeb 26, 2025Montara TherapeuticsCalifornia · San Francisco$20.0MFeb 26, 2025CerilloVirginia · Charlottesville$1.1MFeb 25, 2025Lyora TherapeuticsMassachusetts · Belmont$525KFeb 25, 2025SynlicoCalifornia · South San Francisco$3.0MFeb 24, 2025Episteme PrognosticsNew York · Brooklyn$550KFeb 21, 2025Infinity BioMaryland · Baltimore$2.0MFeb 18, 2025Trinity Nuclein Series C QP InvestorsTexas · Southlake$1.0MFeb 18, 2025EnZeta ImmunotherapiesFlorida · Coral Gables$840KFeb 17, 2025Maxymune TherapeuticsCalifornia · Los Altos$2.7MFeb 11, 2025Grace TherapeuticsNew Jersey · Princeton$15.0MFeb 10, 2025Newleos TherapeuticsMassachusetts · Boston$93.4MFeb 10, 2025OncocyteCalifornia · Irvine$21.7MFeb 10, 2025Tectonic TherapeuticMassachusetts · Watertown$185.0MFeb 5, 2025Resolute ScienceCalifornia · San Diego$2.9MFeb 3, 2025ChromaCodeCalifornia · Carlsbad$3.8MJan 30, 2025ScorpiusNorth Carolina · Morrisville$600KJan 30, 2025Latigo BiotherapeuticsCalifornia · Thousand Oaks$50.0MJan 28, 2025Liberation LabsNew York · New York$52.0MJan 28, 2025NRX PharmaceuticalsDelaware · Wilmington$3.5MJan 27, 2025Aer TherapeuticsNorth Carolina · Raleigh$5.0MJan 24, 2025Allay TherapeuticsCalifornia · San Jose$45.0MJan 24, 2025Revi Life SciencesTexas · Austin$340KJan 22, 2025seqWellMassachusetts · Beverly$12KJan 15, 2025SyenexIllinois · Evanston$8.7MJan 13, 2025BiocontrolMinnesota · Saint Paul$7.1MJan 10, 2025CarnaMassachusetts · Boston$9.1MJan 3, 2025BioPhoundryNorth Carolina · Chapel Hill$1.1MDec 10, 2024SyncromuneFlorida · Fort Lauderdale$144.8MDec 3, 2024Autoimmunity Biologic SolutionsTexas · Houston$3.2MNov 8, 2024EMGenisysTexas · Houston$521KSep 25, 2024Nok TherapeuticsPennsylvania · Cranberry Twp.$751KSep 24, 2024Elastrin TherapeuticsSouth Carolina · Greenville$500KSep 11, 2024TellBioMassachusetts · Andover$1.0MSep 4, 2024Celestial TherapeuticsCalifornia · Irvine$850KSep 3, 20243X GeneticsMassachusetts · Worcester$3.2MAug 5, 2024NGM BioCalifornia · South San Francisco$142.0MJul 5, 2024Trailhead BiosystemsOhio · Beachwood$40.6MJun 21, 2024Jabez BiosciencesPennsylvania · Cranberry Twp.$31KJun 11, 2024Agile GxP TechnologiesRhode Island · Providence$825KJun 4, 2024IVIEW TherapeuticsNew Jersey · Cranbury$9.2MMay 14, 2024Chimeron BioPennsylvania · Philadelphia$12.8MMar 25, 2024Third PoleMassachusetts · Waltham$16.9MMar 18, 2024AlzheonMassachusetts · Framingham$126.3MFeb 27, 2024Modulate BioMassachusetts · Allston$785KFeb 11, 2024BiomakersDelaware · City of Dover, County of Kent$5.9MJan 26, 2024Porosome TherapeuticsMassachusetts · Boston$3.6MSep 8, 2023Quanta TherapeuticsCalifornia · South San Francisco$76.2MMay 10, 2023Contamination Source IdentificationPennsylvania · Hershey$2.1MApr 19, 2023Nexo TherapeuticsColorado · Littleton$60.0MNov 15, 2022Aminex TherapeuticsWashington · Kenmore$15.1MOct 25, 2022RNAV8 BIOCalifornia · Laguna Niguel$2.0MMay 9, 2022Pinteon TherapeuticsMassachusetts · Newton Centre$29.2MJan 7, 2022OmnioxCalifornia · San Francisco$24.1MAug 1, 2016AufbauBiotechnology company focused on creating innovative…N/A—Blue water biotechnology engineering (macau)Activated sludge process for treating wastewaterN/A—PluriPlacenta-derived cell therapiesN/A—Voxcell BioInnovation3D bioprinted tumor models for drug testingN/A—Zhongrong technologyEthyl acetate and fine chemicals for industryN/A—Zucara TherapeuticsDaily drug to prevent insulin-induced hypoglycemiaN/A—

All 256 companies · most recent filing first

Biotech by state

Biotech in California64Biotech in Massachusetts49Biotech in Florida16Biotech in Texas15Biotech in New York14Biotech in Maryland13Biotech in Pennsylvania13Biotech in New Jersey9Biotech in Washington9Biotech in North Carolina7Biotech in Colorado6Biotech in Michigan4Biotech in Minnesota4Biotech in Connecticut3Biotech in Delaware3Biotech in Virginia3

Browse by state

California353Massachusetts156New York155Texas126Florida106Washington82Delaware72Colorado62