Updated Oct 7, 2026

Funded startups in Massachusetts

Every company below filed a Form D with the SEC. Amounts are as reported on the filing, not estimates.

Updated Oct 7, 2026

Companies: 154
Total raised: $4.11B
Filings: 189
Median round: $5.0M
Cities: 49

Most recent filings

154

Company

Sector

City

Last filing

Latest round

AxelyfBiotech · Chestnut HillRNA medicines for solid tumors and autoimmune disease

ArkeaBioBiotech · CharlestownVaccine that cuts methane emissions from cattle

Didge NXRobotics · BostonJobsite robots that capture daily construction progress

LabyrinthAIRobotics · SomervilleTraining data collection and labeling for robotics

Armory TechnologiesHardware · WorcesterFolded composite panels for truck bodies and trailers

Lovable LabsAI · BostonChat-based builder for full-stack web apps

Boston

Jul 31, 2026

$382.5M

Quantum Network TechnologiesHardware · BostonEntangled photon sources for quantum networks

NextPoint TherapeuticsBiotech · CambridgeAntibodies against the B7-H7 checkpoint in cancer

Circinus Medical TechnologyHealthcare · ConcordHandheld navigation for spinal screw placement

MagnendoHealthcare · NewtonMagnetically steered robotic guidewires for stroke care

Cue BiopharmaBiotech · BostonBiologics that modulate disease-specific T cells

Code MetalBostonVerified translation of AI-generated and legacy code

BluStreamSaaS · WorcesterAutomated messages to customers after a product sale

LifewardHealthcare · HudsonRobotic exoskeletons for spinal cord injury and stroke

Farsight AIAI · CambridgeAI that drafts pitch decks and models for bankers

Cambridge

Jul 2, 2026

$10.0M

Infinite CoolingCleantech · MaldenCooling tower retrofit that captures water from the plume

TireTutorSaaS · BrooklineShop management and ecommerce for independent tire dealers

AdvanCellBiotech · CambridgeLead-212 alpha therapies for prostate and other cancers

CoreMapHealthcare · BurlingtonHigh-density mapping catheter for atrial fibrillation

CoristaHealthcare · ConcordDigital pathology slide and case management

Qlaris BioBiotech · DedhamEye drops that lower eye pressure in glaucoma

Syndic8 DMSSaaS · BostonProduct content syndication to online retail channels

SangteraRobotics · LowellMicrohydraulic actuators for robot hands and chip placement

Walden RoboticsRobotics · CambridgeTwo-armed robots for factory and warehouse work

LinqAlphaFintech · CambridgeAI research agents for hedge funds and asset managers

ScvHardware · South DeerfieldCellular IoT connectivity for commercial facility devices

X1 BiotechBiotech · NeedhamRUNX1 inhibitor for inherited small-vessel brain disease

Fleet RoboticsRobotics · CharlestownOnboard robots that clean and inspect ship hulls

UmajinSaaS · BostonLow-code builder for 3D, AR and IoT apps

Portal BiotechnologiesBiotech · ArlingtonMechanical cell delivery for RNA and gene editors

VerveRobotics · CambridgePowered soft exosuit that eases lifting for workers

Ice GemsHardware · WilbrahamLicensed combustion engine designs and modeling software

Remedium BioBiotech · NeedhamDose-adjustable gene therapy for obesity and osteoarthritis

BlitzyAI · CambridgeAI agents that modernize large enterprise codebases

Cambridge

May 1, 2026

$188.8M

Tycho AIDefense · CambridgeGPS-free navigation chips for military drones

NeurunAI · BeverlyAI concierge for marathons and large events

Beverly

Apr 30, 2026

$100K

Climb BioBiotech · Wellesley HillsB-cell depleting antibodies for autoimmune disease

CircuitHubHardware · South DeerfieldOn-demand circuit board assembly with instant quotes

ScitaraSaaS · MarlboroughSoftware that connects lab instruments and data systems

AxoftBiotech · CambridgeSoft-material brain implants for stable neural recording

Enveric BiosciencesBiotech · CambridgeNon-hallucinogenic neuroplasticity drugs for depression

Consensus NLPAI · BostonAI search engine for peer-reviewed research

Boston

Apr 16, 2026

$29.7M

AcuminoRobotics · BostonRobot models for dexterous factory sorting and packing

Elemental MachinesSaaS · CambridgeSensors and monitoring for lab equipment

JuliaHubAI · BostonCloud platform for Julia simulation and modeling

Boston

Apr 10, 2026

$46.7M

Zapata QuantumInfrastructure · BostonQuantum application development and benchmarking software

Foundation Alloy Technology ExplorationsHardware · CambridgeMetal alloys and parts made from powder without melting

ColdSnapConsumer · BillericaCountertop machine that freezes single-serve ice cream pods

Alloy TherapeuticsBiotech · WalthamTransgenic mice for human antibody discovery

Stipple BioBiotech · CambridgeCancer drugs aimed at tumor-specific cell surface markers

The Embedded CompanyFintech · ConcordQuote-to-bind insurance flows inside partner sites

PulmatrixBiotech · FraminghamInhaled dry powder drugs for migraine and lung disease

Myra EB SystemsSaaS · BoxboroughAI software suite for pharma manufacturing and supply chain

Canal BiosciencesBiotech · LowellSequencing library prep that keeps native DNA ends intact

NeosomaHealthcare · GrotonAI brain MRI tumor mapping for neuro-oncology teams

AptaminoBiotech · CambridgeOral delivery of antibody drugs via protein design

CardioNexaHealthcare · NewtonLDL management service for heart attack and stroke patients

DomainGRCSaaS · DanversSecurity and compliance software for health tech companies

PacegenixBiotech · CambridgeProdrugs for atrial fibrillation and fast heart rates

Sprout LabsEdtech · NeedhamVoice AI reading program for kids with dyslexia

LambentProptech · SuttonBuilding occupancy analytics from existing Wi-Fi

CavilinQHardware · CambridgePhotonic links that connect separate quantum processors

Consano BioBiotech · BurlingtonBiologic therapies for orthopedic injuries

Luminous RoboticsRobotics · BostonRobots that install panels on utility-scale solar farms

Dnp TherapeuticsBiotech · CambridgeEarly-stage therapeutics company based in Cambridge, Massachusetts…

IxcelaHealthcare · BeverlyAt-home gut health blood test with dietitian care

Vaxess TechnologiesBiotech · CambridgeDissolvable microarray patches for vaccines

HavocAIDefense · BostonLow-cost autonomous boats and fleet control software

Inflammasome TherapeuticsBiotech · NewtonInflammasome inhibitor implants for geographic atrophy

NodarRobotics · ConcordLong-range stereo camera depth sensing for vehicles

LOOP ShuttleConsumer · HinghamApp-booked van rides for kids to sports and activities

Aevius LabsHealthcare · BostonFoundation model for whole patient medical records

Purlin EnterprisesProptech · HinghamReal estate deal software from home search to closing

Pi HealthHealthcare · CambridgeUnified clinical trial software for sponsors and sites

Filter LabsOther · CambridgeSpecializes in delivering high-quality, location-specific data…

Entact BioBiotech · WatertownOral drugs that enhance proteins instead of blocking them

HolobiomeBiotech · BostonGut bacteria probiotics aimed at depression

QuantumSafe Data SystemsCybersecurity · NorwellOne-time pad encryption for private enterprise networks

Minutes MojoFintech · GloucesterBookkeeping software and service for franchisees

Medici TherapeuticsBiotech · BostonTumor-infiltrating lymphocyte cell therapy for cancer

7AICybersecurity · BostonAI agents that investigate security alerts

Patriot Creek Marine ConceptsOther · SommervilleFlorida-based corporation established in 2013, operating within the…

Phio PharmaceuticalsBiotech · MarlboroughImmune-modulating cancer drugs in clinical trials

NotarizeSaaS · BostonRemote online notarization and identity verification

Beacon BiosignalsHealthcare · BostonEEG analytics and home sleep tests for drug trials

GelMEDIXBiotech · CambridgeHydrogel-delivered cell therapy for geographic atrophy

Viken DetectionDefense · BurlingtonHandheld X-ray scanners for finding contraband

Nirrin TechnologiesBiotech · BillericaLaser spectroscopy for real-time bioprocess measurement

NovolyzeSaaS · CambridgeFood safety and sanitation software for food makers

Dewpoint TherapeuticsBiotech · BostonSmall-molecule drugs that target biomolecular condensates

Tinos TherapeuticsBiotech · CambridgeRNA-targeted small-molecule drugs for glioblastoma

G2MintLogistics · HudsonFreight rating and transportation management software

Lapix TherapeuticsBiotech · BostonOral drugs that restore immune tolerance in autoimmunity

InstyllaHealthcare · BedfordHydrogel liquid embolic that cuts blood flow to tumors

NeutrolisBiotech · CambridgeEnzymes that clear neutrophil traps in autoimmune disease

TagupDefense · BostonAI sustainment and parts forecasting for military logistics

Syntis BIOBiotech · BostonOral pill that mimics gastric bypass for weight loss

Odyssey TherapeuticsBiotech · BostonTranscription factor drugs for autoimmune disease

WyebotInfrastructure · MarlboroAI troubleshooting for enterprise Wi-Fi networks

CreatioSaaS · BostonNo-code CRM and workflow automation

Strand TherapeuticsBostonProgrammable mRNA therapies for solid tumors

Antares TherapeuticsHealthcare · BostonLeading specialty pharmaceutical company focused on the creation and…

Faster OutcomesAI · WalpoleTechnology company dedicated to revolutionizing legal workflows using…

Walpole

Apr 11, 2025

$550K

PhASTBiotech · BostonSingle-cell imaging for fast antibiotic susceptibility tests

AlleviateHealthcare · BrightonAt-home massage tools for musculoskeletal pain

Abside NetworksTelecom · ConcordRadio units for private LTE and 5G networks

Ernexa TherapeuticsBiotech · CambridgeOff-the-shelf stem cell therapy for ovarian cancer

Grain EcosystemCleantech · QuincySoftware for funding and certifying biochar projects

Bridgeline DigitalSaaS · WoburnWeb content, commerce and marketing software

IncentivioSaaS · BostonLoyalty, online ordering and marketing for restaurants

QmbHealthcare · BostonMedical billing and claims follow-up for providers

FhirengineHealthcare · BostonUtilization management software for payers and providers

GAI InsightsAI · NewtonGenerative AI advisory and buyer guides for enterprises

Newton

Mar 8, 2025

$585K

OttometricAI · WalthamAI test data validation for driver assistance systems

Waltham

Mar 7, 2025

$9.5M

Sports Innovation LabMedia · BostonFan behavior research for sports organizations

Amplified IndustriesEnergy · BostonWireless sensors and AI monitoring for oil wells

VulnCheckCybersecurity · LexingtonReal-time exploit and vulnerability intelligence

DeepkinetiXBiotech · CambridgeAI pharmacokinetic modeling for drug dosing

GridFlowEnergy · AlbuquerqueLithium-sulfur flow batteries for grid storage

Patient Discovery SolutionsHealthcare · BostonSocial needs screening for oncology practices

Equilibrium EnergyCleantech · BostonAI tools for managing energy portfolios and trading

Lyora TherapeuticsBiotech · BelmontClinical-stage biotechnology company dedicated to developing…

Machine CoverFintech · ManchesterParametric insurance tools for carriers and brokers

MetamagneticsDefense · MarlboroughAuto-tuning RF filters that block interference

Newleos TherapeuticsBiotech · BostonDrugs for anxiety and substance use disorders

Tectonic TherapeuticBiotech · WatertownProtein drugs targeting G protein-coupled receptors

TegoLogistics · WalthamTracking and lifecycle records for high-value assets

MagLev AeroInfrastructure · BostonLow-noise maglev propulsion for electric aircraft

NanopathHealthcare · CambridgeRapid molecular tests for women's health

Via ScienceAI · SomervilleTools to analyze confidential data without sharing it

Somerville

Jan 23, 2025

$28.4M

MacroCycle TechnologiesCleantech · CambridgePlastic recycling technology

seqWellBiotech · BeverlyDNA library prep for high-throughput sequencing

CarnaBiotech · BostonSmall-molecule drug discovery

Glimpse EngineeringCleantech · SomervilleCT scanning that finds defects in battery cells

Altaeros EnergiesTelecom · SomervilleAutonomous tethered aerostats for remote connectivity

KemlabHardware · WoburnPhotoresists for semiconductor manufacturing

Epicore BiosystemsHealthcare · CambridgeSweat-sensing wearable for worker hydration

Scripta InsightsHealthcare · WellesleyAnalytics that lower pharmacy benefit costs

Ocean OrthopedicsHealthcare · WestportOrthopedic care and sports medicine

Chasm Advanced MaterialsHardware · CantonMaterials science company specializing in the development and…

TellBioBiotech · AndoverMicrofluidic capture of circulating tumor cells from blood

Everbridge ParentSaaS · BurlingtonCritical event management and emergency alerts

3X GeneticsBiotech · WorcesterLong-read tests for repeat expansion genetic disorders

PLATFORM GolfHardware · NeedhamTilting putting and swing platforms for golf simulators

Form HealthHealthcare · BostonVirtual obesity care with physicians and dietitians

Third PoleBiotech · WalthamPortable, tankless inhaled nitric oxide therapy

AlzheonBiotech · FraminghamOral Alzheimer's drug targeting amyloid oligomers

Modulate BioBiotech · AllstonSmall-molecule drugs for essential tremor and epilepsy

Content RavenSaaS · MarlboroughSecure video and document delivery for sales teams

PaymentWorksFintech · BostonSupplier onboarding that blocks payment fraud

GivingaSaaS · BostonSoftware for running corporate giving programs

Porosome TherapeuticsBiotech · BostonTherapies that restore the cell's secretory machinery

FlexxboticsRobotics · BostonSoftware that coordinates factory robots and CNC machines

Pinteon TherapeuticsBiotech · Newton CentreAntibody against toxic tau for brain injury and Alzheimer's

All 154 companies · most recent filing first