LNS8801
Small-Molecule TherapeuticLNS8801 is an orally administered, small-molecule agonist of the G protein-coupled estrogen receptor (GPER). It is being developed for cancer treatment and functions by rapidly depleting c-Myc protein levels, leading to antitumor activity and demonstrating target engagement in clinical trials.
- Oral small-molecule agonist of GPER
- Rapidly depletes c-Myc protein levels to induce antitumor activity
- Has shown durable clinical benefit in trials
- Safe and well-tolerated in clinical studies