Placental protein immunotherapy program
Preclinical biologic therapeuticAn early-stage drug program derived from a natural human protein produced by the placenta during pregnancy and expressed in the thymus, developed as an immunosuppressive therapeutic for solid organ transplant rejection and autoimmune disorders.
- Based on a naturally occurring human placental protein
- Impairs effector T cells
- Promotes proliferation of regulatory T cells
- Downregulates B cell function, relevant to antibody-mediated rejection