Placental protein immunotherapy program
Preclinical biologic therapeutic
An early-stage drug program derived from a natural human protein produced by the placenta during pregnancy and expressed in the thymus, developed as an immunosuppressive therapeutic for solid organ transplant rejection and autoimmune disorders.
- Based on a naturally occurring human placental protein
- Impairs effector T cells
- Promotes proliferation of regulatory T cells
- Downregulates B cell function, relevant to antibody-mediated rejection
- Intellectual property exclusively licensed from Cedars-Sinai Medical Center
Built for
Solid organ transplant recipients, including kidney transplant patients with chronic antibody-mediated rejection, and patients with autoimmune disorders.