Skip to content
Companies

ORF Biologics

Custom recombinant proteins and contract manufacturing

Raised to date

$1.7M

of $2.5M offered across 1 Form D filing

Still open
$766K
Investors
17
Last filed
Jul 31, 2026

About

ORF Biologics is a Tiffin, Iowa biotechnology company that designs, develops and manufactures recombinant proteins and other advanced biologics for research and therapeutic use. It supplies both catalog (off-the-shelf) and custom biologics, cell lines and growth media, antibodies, and chromatography resins, and also runs contract development and manufacturing programs for pharma and biotech customers. Its work targets infectious disease, neurodegeneration, regenerative medicine and biosecurity applications. Cosmo Bio USA began distributing ORF Biologics products in the United States in February 2026.

Combines protein engineering and synthetic biology with GMP-aware, scalable expression so that proteins described as hard to make can be produced at both small research and bulk manufacturing volumes from the same process.

Funding

  • EquityFiled Jul 31, 2026Form D
    $1.7M/ $2.5M

Product

Custom Biologics

Biologics manufacturing

Made-to-order recombinant proteins and other biologics engineered, expressed and purified to a customer's specification, from plasmid design and genetic engineering through scalable expression and quality control.

  • Custom protein engineering and design
  • Plasmid manufacturing and genetic engineering
  • Scalable protein expression from small to bulk orders

Built for

Pharmaceutical and biotechnology companies plus academic and government research labs working in infectious disease, neurodegeneration, regenerative medicine and biosecurity

People on file