Primary Bioscience is a Seattle-based life science company developing a single-molecule protein sequencing device for comprehensive, multi-biomarker screening. The instrument uses nanopore-based sensing reengineered from DNA sequencing to read proteins directly, without antibodies or affinity reagents. The company aims to sequence every protein in a sample, including hard-to-detect variations such as single-residue substitutions, splice variants and post-translational truncations. It is positioning the platform both as a multi-cancer early detection tool and as a proteomics research instrument.