ART26.12
Small-molecule drug candidate
A potent and selective oral inhibitor of fatty acid binding protein 5 (FABP5), an intracellular lipid transport protein, developed as a peripherally acting non-opioid analgesic. Its lead indication is chemotherapy-induced peripheral neuropathy (CIPN), with additional interest in other neuropathic pain, psoriasis, breast, prostate and cervical cancer, and generalized anxiety.
- Selective FABP5 inhibitor, first-in-class mechanism
- Peripherally acting, non-opioid
- Completed Phase 1 single-ascending-dose and food-effect studies
- Reported wide therapeutic window and predictable pharmacokinetics
- Three issued patents with 14 applications pending
Built for
Oncologists, pain specialists, and the patients they treat, reached through pharmaceutical partners and payers once candidates are approved.