Skip to content

Canal Biosciences

Sequencing library prep that keeps native DNA ends intact

Raised to date

$2.3M

of $3.2M offered across 1 Form D filing

Still open
$915K
Investors
18
Last filed
Apr 13, 2026

About

Canal Biosciences develops DNA library preparation technology for next-generation sequencing. Its proprietary TrueLink platform uses its own enzymes and adaptors in a simultaneous dual-ligation workflow that attaches sequencing adaptors directly to native DNA ends, skipping end repair. The company also offers DISTAL-seq and DISTAL-methyl-seq products aimed at liquid biopsy and methylation sequencing. Products are sold for research use only.

Ligates adaptors to native DNA ends without end repair or A-tailing, preserving true mutations, terminal structure, single-stranded molecules and methylation signals at fragment ends.

Funding

  • EquityFiled Apr 13, 2026Form D
    $2.3M/ $3.2M

Product

TrueLink

Sequencing library preparation reagent kit

NGS library prep platform using proprietary enzymes and adaptors in a dual-ligation workflow that attaches adaptors directly to native DNA ends.

  • Simultaneous dual-ligation workflow
  • No end repair or A-tailing
  • Preserves native terminal structure and single-stranded molecules

Built for

Genomics researchers running next-generation sequencing, including liquid biopsy and methylation studies

People on file