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Funded Biotech startups in Massachusetts

49 biotech startups in Massachusetts have filed a Form D with the SEC and together report $1.66B raised. AdvanCell has the largest latest round, at $218.3M. Amounts are as reported on the filing, not estimates.

Updated Oct 7, 2026
Companies
49
Total raised
$1.66B
Filings
63
Median round
$7.6M
Cities
22

Most recent filings

49
AxelyfChestnut Hill$2.6MOct 7, 2026ArkeaBioCharlestown$15.0MSep 28, 2026NextPoint TherapeuticsCambridge$33.7MJul 22, 2026Cue BiopharmaBoston$50.0MJul 13, 2026AdvanCellCambridge$218.3MJun 30, 2026Qlaris BioDedham$3.9MJun 12, 2026X1 BiotechNeedham$40KMay 20, 2026Portal BiotechnologiesArlington$9.0MMay 15, 2026Remedium BioNeedham$1.5MMay 6, 2026Climb BioWellesley Hills$110.1MApr 29, 2026AxoftCambridge$34.2MApr 22, 2026Enveric BiosciencesCambridge$5.0MApr 17, 2026Alloy TherapeuticsWaltham$30.0MMar 31, 2026Stipple BioCambridge$65.1MMar 31, 2026PulmatrixFramingham$1.0MMar 26, 2026Canal BiosciencesLowell$2.3MMar 18, 2026AptaminoCambridge$8.0MMar 17, 2026PacegenixCambridge$22.5MMar 11, 2026Consano BioBurlington$34.8MMar 6, 2026Dnp TherapeuticsCambridge$470KMar 5, 2026Vaxess TechnologiesCambridge$57.3MMar 4, 2026Inflammasome TherapeuticsNewton$13.2MFeb 27, 2026Entact BioWatertown$10.0MJan 8, 2026HolobiomeBoston$10.0MDec 24, 2025Medici TherapeuticsBoston$14.8MNov 20, 2025Phio PharmaceuticalsMarlborough$1.4MNov 4, 2025GelMEDIXCambridge$747KOct 1, 2025Nirrin TechnologiesBillerica$6.7MSep 23, 2025Dewpoint TherapeuticsBoston$77.2MSep 9, 2025Tinos TherapeuticsCambridge$2.3MSep 4, 2025Lapix TherapeuticsBoston$2.2MJul 21, 2025NeutrolisCambridge$3.5MJun 20, 2025Syntis BIOBoston$25.0MJun 17, 2025Odyssey TherapeuticsBoston$214.0MJun 16, 2025PhASTBoston$3.5MApr 11, 2025Ernexa TherapeuticsCambridge$7.2MMar 31, 2025DeepkinetiXCambridge$1.0MMar 3, 2025Lyora TherapeuticsBelmont$525KFeb 25, 2025Newleos TherapeuticsBoston$93.4MFeb 10, 2025Tectonic TherapeuticWatertown$185.0MFeb 5, 2025seqWellBeverly$12KJan 15, 2025CarnaBoston$9.1MJan 3, 2025TellBioAndover$1.0MSep 4, 20243X GeneticsWorcester$3.2MAug 5, 2024Third PoleWaltham$16.9MMar 18, 2024AlzheonFramingham$126.3MFeb 27, 2024Modulate BioAllston$785KFeb 11, 2024Porosome TherapeuticsBoston$3.6MSep 8, 2023Pinteon TherapeuticsNewton Centre$29.2MJan 7, 2022

All 49 companies · most recent filing first

Biotech by state

Biotech in California64Biotech in Florida16Biotech in Texas15Biotech in New York14Biotech in Maryland13Biotech in Pennsylvania13Biotech in New Jersey9Biotech in Washington9Biotech in North Carolina7Biotech in Colorado6

Cities in Massachusetts

Boston44Cambridge30Concord5Burlington4Marlborough4Needham4Newton4Somerville4Waltham4Beverly3