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Companies

Cognos Therapeutics

Implantable pump that delivers drugs into the brain

Raised to date

$250K

of $2M offered across 1 Form D filing

Still open
$1.8M
Last filed
Jul 2, 2026

About

Cognos Therapeutics is an Inglewood, California medical device company developing SINNAIS, an implantable smart pump that delivers drugs directly into the brain's ventricles through the cerebrospinal fluid. The device pairs a piezoelectric micropump capable of one-microliter dosing with optical sensors and microdialysis that read CSF biomarkers such as beta-amyloid and tau, and transmits results wirelessly to a physician's tablet for remote monitoring and reprogramming. Intended applications include brain and spinal tumors, CAR-T cell therapy delivery, and neurodegenerative conditions such as Alzheimer's disease. The company is running a clinical and research collaboration with Massachusetts General Hospital and Harvard on delivering therapeutics to the brain via the device.

No implantable pump is currently marketed for intraventricular treatment of CNS disease; SINNAIS combines metronomic intraventricular dosing with real-time CSF biomarker biofeedback, claims ten times the delivery accuracy of existing implantable pumps, and adds a flushing port that addresses the catheter clogging that plagues current devices.

Funding

  • Security to be acquiredFiled Jul 2, 2026Form D
    $250K/ $2M

Product

SINNAIS implantable smart pump

Implantable medical device

An AI-driven implantable pump that infuses therapeutics directly into the brain's ventricles along the cerebrospinal fluid pathway, while sampling and analyzing CSF in real time and reporting wirelessly to the treating physician.

  • Piezoelectric micropump delivering precise one-microliter doses, a claimed ten-fold accuracy improvement over current implantable pumps
  • Optical sensors and microdialysis that measure CSF biomarkers including beta-amyloid and tau in real time
  • Proprietary biological filter that removes protein debris and returns cleaned fluid to the spinal canal

Built for

Neurosurgeons and neuro-oncology centers treating brain and spinal tumors, plus clinicians and drug developers working on Alzheimer's, Parkinson's, epilepsy, stroke and other central nervous system conditions

People on file