PIPr Therapeutics, Inc. (PIPr Tx) is a preclinical-stage biotechnology company based in Durham, North Carolina. The company describes its work as pioneering precision metalloprotease inhibitors. It is led by CEO and co-founder Heather Madsen, a pharmaceutical research executive and Hatteras Venture Partners partner, and its public website is still a pre-launch placeholder with no disclosed pipeline or lead candidates.
The company positions its approach as precision inhibition of metalloproteases - selective targeting of individual enzymes in a protease family whose earlier broad inhibitors were limited by off-target activity. No further differentiation has been disclosed publicly.